Enduring a hardscrabble existence as the children of alcoholic and absent parents, four siblings from a coastal Mississippi town prepare their meager stores for the arrival of Hurricane Katrina while struggling with such challenges as a teen pregnancy and a dying litter of prize pups.

Conceived to provide a bone marrow match for her leukemia-stricken sister, teenage Kate begins to question her moral obligations in light of countless medical procedures and decides to fight for the right to make decisions about her own body. New York Times bestselling author Jodi Picoult tells the emotionally riveting story of a family torn apart by conflicting needs and a passionate love that triumphs over human weakness. Anna is not sick, but she...